Clinical application of Helicobacter pylori vaccine

According to the information on the website of the State Food and Drug Administration (CFDA), the clinical application of class 1 new drug of the Institute of bioengineering, Academy of Military Medical Sciences of the people's Liberation Army for oral Helicobacter pylori genetic engineering live carrier vaccine was accepted It is worth mentioning that Yueyang Xingchang "oral Recombinant Helicobacter pylori vaccine" has been approved as a new drug certificate in 2009, but it has not been industrialized yet Helicobacter pylori can cause chronic gastritis, gastric ulcer, duodenal ulcer, gastric mucosa related lymphoma and other upper gastrointestinal diseases In 1994, WHO has confirmed that it is closely related to the occurrence of gastric cancer, and listed it as a kind of carcinogen According to relevant analysis, more than 600 million people are infected with Helicobacter pylori in China, and about 200000 people die of gastric cancer every year Due to the lack of appropriate animal models, the lack of effective treatment of Helicobacter pylori, almost all based on clinical experience, due to regional and population differences have greater limitations It is worth mentioning that the class 1 new drug "oral Recombinant Helicobacter pylori vaccine" developed by Wuhu Kangwei, a joint-stock subsidiary of Yueyang Xingchang, has been approved as a new drug certificate in April 2009, but the product has not yet been industrialized due to the technical handover In response, Yueyang Xingchang pointed out that the industrialization capacity building project of oral Recombinant Helicobacter pylori vaccine new products is expected to complete equipment installation, commissioning and trial production in 2015, and the products will be launched in 2017 According to the CFDA website, at present, only two institutes, Wuhu Kangwei and Bioengineering Institute of Military Medical Sciences of the people's Liberation Army, are involved in the research and development of Helicobacter pylori vaccine in China.