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Compared with the general population, people with severe mental illness, including schizophrenia, bipolar disorder and major depression, including (SMI) in patients with heart vascular risk factors earlier, the future is more prone to heart failure (HF)
.
Recently, a research article was published in Circ-Heart Fail, an authoritative journal in the cardiovascular field.
Researchers aimed to investigate the association between with/without SMI and long-term HF outcome
.
Researchers identified HF patients with and without SMI in the Duke University health system from 2002 to 2017, and used multivariate Cox regression to assess the main outcome of all-cause mortality
.
Secondary outcomes included the use rate of implantable cardioverter defibrillators, cardiac resynchronization therapy, left ventricular assist device implantation rate, and heart transplant rate
The researchers included 20,906 HF patients (SMI, n=898; non-SMI, n=20008)
.
The clinical manifestations of SMI patients are 7 years earlier than those of patients without SMI
Thus, SMI is associated with adverse HF outcomes in males rather than females
.
Although patients with and without SMI have the same chance of undergoing HF surgery, patients with SMI have a higher postoperative mortality rate
SMI is associated with adverse HF outcomes in males rather than females
Original source:
Christoffer Polcwiartek,et al.
