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Figure: The extracellular vesicles (EV) secreted by normal cilia (left) are larger than those secreted by normal cilia
Approximately one in every 1,000 people in the world suffers from ciliary disease
Problems with primary cilia can cause a series of symptoms
The primary cilia are small and extend from the cell surface like eyelashes
Bardet-Biedl syndrome affects one in every 25,000 people in the global population, so it is relatively rare
Cilia control communication between cells
For a long time, it has been thought that primary cilia are degenerated organelles and therefore redundant
Dr.
Successful cooperation with other biological teams
This main function of extracellular vesicles was determined in collaboration with the team of Professor Eva-Maria Kr?mer-Albers from the JGU Institute of Developmental Biology and Neurobiology
Professor René Ketting of the Institute of Molecular Biology (IMB) also participated in the project.
Article title
Bardet-Biedl syndrome protein regulates the release of biologically active extracellular vesicles
