 Home > Medical News > Medicines Company News > Chuangsheng Group announced that its new anti-PD-L1 and TGF-β bifunctional antibody drug TST005 has been approved by the U.S. FDA for clinical trials

Chuangsheng Group announced that its new anti-PD-L1 and TGF-β bifunctional antibody drug TST005 has been approved by the U.S. FDA for clinical trials

 Last Update: 2021-07-08
 Source: Internet
 Author: User

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Chuangsheng Group, an international biopharmaceutical company in the clinical stage with the ability to integrate the entire process of biopharmaceutical R&D, clinical and process development and production, today announced that its new anti-PD-L1 and TGF-β bifunctional antibody (TST005) new drug has been obtained The U.
S.
Food and Drug Administration (FDA) is licensed to carry out clinical trials
.

TST005 is a bifunctional antibody that simultaneously targets two pathways commonly used by cancer cells to escape immune suppression, namely transforming growth factor-β (TGF-β) and programmed cell death ligand-1 (PD-L1)
.

TST005 is composed of a high-affinity PD-L1 antibody and an engineered TGF-β receptor type II protein fused to its C-terminus

"TST005 is one of the few leading drug candidates targeting PD-L1/TGF-β dual-functional antibodies currently under clinical development in the world
.

" Shi Ming, Executive Vice President, Head of Global R&D and Chief Medical Officer of Chuangsheng Group Dr.

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