Chinese and foreign scientists discover important intestinal flora affecting human health

scientists from four chinese research institutes and Imperial College of Technology in the United Kingdom, after three years of joint research, in the intestinal flora and humanhealthresearch made a major breakthrough in the study of the relationship between the intestinal flora and the human body, identified the intestinal body involved in the body's metabolic process escant some important bacteriaThe study has been published in theProceedings of the National Academy of Sciences (PNAS , an international lymicing academic journalReporters learned from Shanghai Jiaotong University, Shanghai Jiaotong University Institute of Systems Biomedical Research,Zhejiang University, the first affiliatedHospital,imperial university of,National Human Genome Research Center and the Chinese Academy of Sciences Wuhan Institute of Physics and Mathematics 5 scientific research and medical institutions of scientists formed a multidisciplinary cross-research team, after nearly 3 years of joint research, a four-year-old Chinese family of seven members of the intestinal microbiome composition and human metabolic characteristics of the bodyThe composition of the intestinal flora affects everyone's healthIt has been found that intestinal microbiome disorders are associated with manydiseases such as diabetes
, obesity Scientists believe that the goal of treating various diseases can be achieved by inventing drugs targeting gut bacteria to correct the structure of the disordered flora But what exactly plays an important role in tens of thousands of bacteria and specifically affects which metabolic pathways are not well understood In recent years, the development of technology from genome to metabolomics has provided a new means to solve scientific problems in this field Using genomic techniques such as bacterial DNA fingerprinting
mapping and genome marker sequencing, the researchers thoroughly and deeply mapped the composition of the seven Chinese members' intestinal flora, and found that although they belonged to the same family
, genetic backgrounds were related to each other, and the living environment was similar , each individual still had its own unique intestinal flora structure characteristics In addition, , researchers also found significant differences in the level of the Chinese's intestinal flora at a level compared to the five Americans previously reported At the same time
, researchers used MRI-itabs-based metabolomics to analyze the composition of metabolites in volunteers' urine to reflect the overall metabolic status of the human body The study found that , certain bacteria in the gut are particularly important for human health For example, a bacterium belonging to the thick-walled baccarat department has a statistical correlation with eight kinds of metabolites in the human body, suggesting that the bacteria plays an important role in participating in the host's multiple metabolic processes This combination of microbial genomics technology and metabgroup technology allows for a more accurate picture of the relationship between bacteria and host metabolism Next, researchers can target these specific gut bacteria and develop new ways to treat diseases by changing their interactions with the host