Chinese Academy of Sciences scholar Nature discovers a new mechanism of immune metabolism for broad-spectrum disease resistance in rice

On December 16, 2021, the top international academic journal Nature published online a research paper entitled "NLRs guard metabolism to coordinate pattern- and effector-triggered immunity" completed by the He Zuhua research group of the Center for Excellence in Molecular Plant Science, Chinese Academy of Sciences, revealing A brand new broad-spectrum immune metabolism regulation network

As one of the world’s staple food crops, rice feeds nearly half of the world’s population

Reasonable and efficient utilization and analysis of rice's broad-spectrum and durable disease-resistant resources is the most economical, effective and environmentally friendly method for preventing and controlling rice blast, and it is also an important strategy to ensure the sustainable development of agriculture

In response to the above problems, the research team comprehensively used experimental technology platforms such as plant pathology, proteomics, genetics, molecules, and biochemistry to identify a new immune regulatory protein PICI1

Through further analysis of the genome data of 3000 rice varieties, it is found that the PICI1 promoter has a natural variation site for indica-japanese differentiation, and this site is associated with the basic resistance of rice blast, which provides new ideas for rice disease resistance breeding And target

With the global warming, the outbreak and prevalence of crop pests and diseases have become more frequent, and the control of pests and diseases through the extensive use of pesticides poses a serious threat to human food safety and the ecological environment, which is one of the major issues that urgently need to be resolved in China's agricultural production

Postdoctoral fellow at the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences Zhai Keran and doctoral student Liang Di are the co-first authors of the paper, and researcher He Zuhua is the corresponding author

Link to the paper: https://