China finds new protein that regulates sperm movement to help study contraceptive vaccine

new progress in contraceptive vaccine research in China
,third military medical university, DrLi Yanfeng and DrHe Wei jointly discovered a new type of fiber-celico-calcium binding proteininvolved in spermexercise and hyperactivation regulation,the results of this study to promote contraceptive vaccine research and in-depth understanding of human reproductive biological behavior of important theoretical significance and potential application valueThe search for and development of a vaccinethat effectively stimulates immune response and thus blocks fertilization is an important goal in the field of reproductive and contraceptive researchIn the past two decades, despite the many advances made by scientists in various countries in basic research in reproductive biology and the discovery of a variety of important proteins closely related to reproduction, no specific and effective target proteins have been found that can be used effectively in human contraceptive vaccinesAfter 8 years of research, DrLi Yanfeng and DrHe Wei of the Third Military Medical University found and identified a new, as-yet-unnamed sperm-specific protein and its genes in human and mouse sperm, which is located in the main segment of the sperm tail, in addition to having significant tissue-specific expression and positioning characteristics, but also has significant calcium binding function and significant phosphoryenic effectThe study found new information about the composition of important proteins formed by fibroblasts during the development of human sperm, and laid the groundwork for the search for potential new targets for contraceptionPreliminary studies suggest that the protein may be of great value in the study of new contraceptivesIn recent years, DrLi Yanfeng and DrHe Wei have published more than 10 research papers on the search for contraceptive target proteins and animal studiesThe discovery of the new gene and protein has been patented in the United States, one of the sites under development(
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