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Studies have shown that patients with cerebral amyloid angiopathy (CAA) are at increased risk of recurrent intracerebral hemorrhage (ICH)
.
Aayushi Garg from the United States studied the recurrence rate of cerebrovascular events in patients with ICH with and without CAA
.
The findings were presented as a poster abstract at the International Stroke Congress 2022 (ISC 2022)
.
The author of this article: Yimaitong ISC report group compiled and organized by Yimaitong, please do not reprint without authorization
.
STUDY INTRODUCTION Using the national readmission database from 2016-2018, we identified hospitalized patients with a primary discharge diagnosis of ICH with or without CAA
.
Inpatients aged >55 years, survival to discharge, and known discharge disposition were included for further analysis
.
Propensity score matching was used to match differences in demographics, comorbidities, and disease severity between CAA and non-CAA groups
.
Survival analyses were performed to assess the incidence of recurrent intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and acute ischemic stroke (AIS) in the propensity-matched group
.
MAIN STUDY RESULTS ➤ A total of 194,290 patients with ICH met the study inclusion criteria; 8,247 had CAA and 186,043 did not
.
After propensity score matching, we identified 7857 CAA hospitalized patients and 7874 non-CAA hospitalized patients
.
During a mean follow-up period of 6 months, CAA patients were associated with ICH [hazard ratio (HR): 3.
4, 95% CI: 2.
6-4.
6, P<0.
001] and SAH (HR: 2.
5, 95% CI: 1.
2-5.
4, P 0.
007) and more likely to be readmitted
.
➤ However, the readmission rate due to AIS was not statistically significantly different (HR: 0.
7, 95% CI: 0.
5-1.
0, p 0.
061) [Figure 1]
.
Figure 1 ➤ Age (HR: 0.
96/age growth rate, 95%CI: 0.
95-0.
98, P<0.
001) and Medicare payer (HR: 3.
23; 95%CI: 1.
92-5.
41, P<0.
001) and intracerebral hemorrhage Readmission was independently related
.
CONCLUSIONS: ICH patients with a secondary diagnosis of CAA were three times more likely to be readmitted for ICH than non-CAA patients
.
Yimaitong compiled from: Recurrent Intracerebral Hemorrhage In Patients With Cerebral Amyloid Angiopathy.
ISC2022.
.
Aayushi Garg from the United States studied the recurrence rate of cerebrovascular events in patients with ICH with and without CAA
.
The findings were presented as a poster abstract at the International Stroke Congress 2022 (ISC 2022)
.
The author of this article: Yimaitong ISC report group compiled and organized by Yimaitong, please do not reprint without authorization
.
STUDY INTRODUCTION Using the national readmission database from 2016-2018, we identified hospitalized patients with a primary discharge diagnosis of ICH with or without CAA
.
Inpatients aged >55 years, survival to discharge, and known discharge disposition were included for further analysis
.
Propensity score matching was used to match differences in demographics, comorbidities, and disease severity between CAA and non-CAA groups
.
Survival analyses were performed to assess the incidence of recurrent intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and acute ischemic stroke (AIS) in the propensity-matched group
.
MAIN STUDY RESULTS ➤ A total of 194,290 patients with ICH met the study inclusion criteria; 8,247 had CAA and 186,043 did not
.
After propensity score matching, we identified 7857 CAA hospitalized patients and 7874 non-CAA hospitalized patients
.
During a mean follow-up period of 6 months, CAA patients were associated with ICH [hazard ratio (HR): 3.
4, 95% CI: 2.
6-4.
6, P<0.
001] and SAH (HR: 2.
5, 95% CI: 1.
2-5.
4, P 0.
007) and more likely to be readmitted
.
➤ However, the readmission rate due to AIS was not statistically significantly different (HR: 0.
7, 95% CI: 0.
5-1.
0, p 0.
061) [Figure 1]
.
Figure 1 ➤ Age (HR: 0.
96/age growth rate, 95%CI: 0.
95-0.
98, P<0.
001) and Medicare payer (HR: 3.
23; 95%CI: 1.
92-5.
41, P<0.
001) and intracerebral hemorrhage Readmission was independently related
.
CONCLUSIONS: ICH patients with a secondary diagnosis of CAA were three times more likely to be readmitted for ICH than non-CAA patients
.
Yimaitong compiled from: Recurrent Intracerebral Hemorrhage In Patients With Cerebral Amyloid Angiopathy.
ISC2022.
