 Home > Biochemistry News > Biotechnology News > Cell’s latest discovery: ruptured cell nucleus promotes cancer cell invasion!

Cell’s latest discovery: ruptured cell nucleus promotes cancer cell invasion!

 Last Update: 2021-09-29
 Source: Internet
 Author: User

Tags

outer membrane function

megaspore mother cell

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Image: Image of human tumor cells invading the collagen matrix

Source: Guilherme Nader/Curie Institute

The nucleus has an important function: to protect the DNA of the cell and enable it to be used normally

New research shows that when cells are compressed and the nucleus temporarily ruptures, DNA comes into contact with an enzyme called TREX1 that destroys DNA

In healthy tissues, cells will show signs of aging and stop dividing

These results reveal the importance of TREX1 enzyme in the development and aging process of breast cancer

The main points of the article:

• Deformed nuclei and DNA damage are enriched in breast cancer micro-invasive foci

Article Abstract

(Biocom)

Original search:

Compromised nuclear envelope 1 integrity drives TREX1-dependent DNA damage and tumor cell invasion

DOI

10.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.