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Scientists have long tried to introduce genetically engineered bacteria into the gut to treat disea.
"I can only say good luck to non-native bacter.
The group devised a solution to this problem by directly engineering.
"We've engineered these bacteria into factories that can live in our microbiome and potentially produce drugs," Zarrinpar sa.
The team first took fecal samples from the host and extracted.
The superpower the team conferred on these specific bacteria was a protein called bile salt hydrolase (BS.
This is a significant improvement over similar treatments using non-native laboratory engineered bacterial strains, where more than one treatment is often requir.
In addition to successfully affecting diabetes in mice, the team was able to make similar modifications to.
While they have demonstrated substantial results, engineering native bacteria presents another set of challeng.
The group is planning to use the technology to find treatments for more diseas.
Original title:
Intestinal Transgene Delivery with Native.
