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    Home > Biochemistry News > Biotechnology News > Cell size and cell membranes may play a key role in regulating the distribution of molecules within cells

    Cell size and cell membranes may play a key role in regulating the distribution of molecules within cells

    • Last Update: 2022-09-09
    • Source: Internet
    • Author: User
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    Picture: Aqueous solution of two polymers (red and green) in test tubes and artificial cells of different sizes



    New research suggests that cell size and cell membranes may play a key


    Artificial cells can be small saviors, such as the COVID-19 mRNA vaccine


    However, creating and manipulating these cells presents many challenges


    This separation, known as liquid-liquid phase separation (LLPS), has become a fundamental mechanism for regulating the biological activity of living organisms


    "Traditionally, as long as the size of the container is 1 micron or micron (one thousandth of a millimeter) or greater, the separation conditions and degree of separation are considered dimension-independent


    The idea of cell size-dependent behavior was proposed in 2012, but the details of the phenomenon remain unclear


    "From experiments like this, we became aware of the subtle differences between membrane-sense molecules and chose the preferred molecule, which is the origin


    What's next? According to Yanagisawa, "The next step is mainly in two directions: one is the physical understanding and formulation of the effects of cell-sized spaces on molecular behavior; The other is used in pharmaceutical and cosmetic applications, taking into account the effects of cell size, using artificial cells


    Article title

    Cell-sized confinement initiates phase separation of polymer blends and promotes fractionation upon competitive membrane wetting


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