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Cell Prolif: LncRNA-AK137033 regulates the Wnt signaling pathway through DNA methylation and inhibits the osteogenic potential of adipose-derived stem cells in diabetic osteoporosis

 Last Update: 2022-01-21
 Source: Internet
 Author: User

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Background: Diabetes mellitus is a systemic metabolic disease characterized by hyperglycemia

Diabetes is a systemic metabolic disease characterized by hyperglycemia

METHODS: A mouse model of DOP was established

Results: The DOP mouse model was successfully established

Conclusion: LncRNA-AK137033 inhibits the osteogenic potential of DOP-ASCs by regulating the level of DNA methylation in the sFrp2 promoter region and regulating the Wnt signaling pathway

LncRNA-AK137033 inhibits the osteogenic potential of DOP-ASCs by regulating the DNA methylation level in the sFrp2 promoter region and regulating the Wnt signaling pathway

LncRNA-AK137033 inhibits the osteogenic potential of adipose-derived stem cells in diabetic osteoporosis by regulating Wnt signaling pathway via DNA methylation.

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