Cell Host Microbe: The Importance of Detecting Neutral antibody activity in patients with COVID19 recovery

2020 May 17 News / BioValley BIOON / --- recently published in the "CellHostMicrobe" magazine article, Professor KantaSubbarao emphasized COVID 19-patient recovered detection and antibody responses as well as the importance of research COVID-19 vaccine in animal modelsneutralizing antibodies to prevent infection by binding to the virus and blocking its ability to infectAfter infection, the host may generate neutralizing antibodies to prevent future infectionsProfessorSubbarao is the head of the US National Institutes of Health Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases American emerging respiratory virus families of 2002 to the 2003 SARS outbreak, how to neutralizing antibodies to prevent infectionProfessor Subbarao said: "We found that mice use a very important phenomenon, namely neutralizing antibody alone is sufficient to protect them from SARS-CoV infection."(Source: Www.pixabay.com)
she also explained the crucial discovery, namely the importance of protein induces "spike" of the virus neutralizing antibodies, as well as several animal testing SARS vaccine candidates

"SARS-CoV and 'spike' SARS-CoV-2 protein having a certain similarity, they can be attached to the same molecule ACE2 in order to achieve the effect of the infection of human cellsNow, by SARS-CoV- animal experiments 2, trying to clear the research and whether antibodies to prevent re-infection"Professor Subbarao said"Previously, we evaluated in clinical trials of two SARS vaccine, and tested a number of other promising vaccine candidate, but because of SARS does not reappear, and therefore not be trackedHowever, based on the SARS the COVID-19 work with a pandemic, but also to the two viruses have multiple features, so we got a lot of experience in terms of SARS vaccine will be applied to study SARS-CoV-2 vaccine"(bio Valley Bioon.com)information source:ImportanceofdetectingneutralizingantibodyresponseinrecoveredCOVID-19patientsoriginal source: Subbarao, K., etal (2020) 1SARS-CoV-2: ANewSongRecallsanOldMelody CellHost & Microbe doi.org/10.1016/j.chom.2020.04.019