Carcinoma-in-situ AIS of early lung cancer

1. Growth is extremely slow, most of which remain stable for more than 10 years.

   
   

2. Failure to break through the basement membrane means that the tumor is confined to the epithelial layer without blood vessels and lymphatics entering, so distant and lymph node metastasis will not occur.

   
   

3. There will be no recurrence after resection and does not affect survival.

   
   

    

The following are all preoperative images of patients with carcinoma in situ diagnosed by my surgery in recent years:

Image features : mostly ground glass shadows <1cm, low density, may have high-risk features such as burrs, vacuoles, and blood vessel passage.

The main characteristics of AIS for carcinoma in situ are as follows:

1. Growth is extremely slow, most of which remain stable for more than 10 years.

   
   

2. Failure to break through the basement membrane means that the tumor is confined to the epithelial layer without blood vessels and lymphatics entering, so distant and lymph node metastasis will not occur.

   
   

3. There will be no recurrence after resection and does not affect survival.

   
   

    

Growth is extremely slow, most of which remain stable for more than 10 years.

Failure to break through the basement membrane means that the tumor is confined to the epithelial layer without blood vessels and lymphatics entering, so distant and lymph node metastasis will not occur.

There will be no recurrence after resection and does not affect survival.

The following are all preoperative images of patients with carcinoma in situ diagnosed by my surgery in recent years:

Image features : mostly ground glass shadows <1cm, low density, may have high-risk features such as burrs, vacuoles, and blood vessel passage.
Generally, even if blood vessels pass, there is no blood vessel curvature, and there may be no obvious high-risk features, but during the follow-up process There is no obvious change.

The treatment principle of AIS: Since cancer in situ grows slowly and will not metastasize, it is not dangerous to the body at this stage.
In 2021, the WHO has excluded cancer in situ from the category of lung cancer.
Together with dysplasia, it is considered to be a precancerous lesion, so It can be removed without surgery.
Generally, based on the size of the nodule, it is recommended to review the chest CT follow-up for 6-12 months.
During the follow-up, if the nodules become larger or the density increases, indicating growth, there is no time for surgery.
If the patient's psychological pressure is relatively large, or the nodule is more than 8mm, with more high-risk features, it can also be directly resected by thoracoscopic surgery.
It should be noted that the AIS of carcinoma in situ is cured after resection, will not recur, and does not require postoperative adjuvant treatment.
It can be said that after removal, they are normal people.