Cancer Cell reviews deep analysis! Dietary strategies for treating cancer!

, June 28, 2020
/PRNewswire/ -- In a recent study published in the International Journal of's Cancer Cell
, scientists from the Francis Research Institute discussed dietary methods for treating cancer and improving the body through dietary changes The concept of therapy response is attractive to many patients, and they have a strong motivation to control certain aspects of treatment, and as researchers gain insight into the metabolic mechanisms of cancer, they are increasingly aware of the importance of nutritional supply to the development and therapeutic response oftumor, which often exhibit diverse metabolic needs, often influenced by a variety of factors, such as tissue origin, microenvironment, andgeneticsfactors, so dietary regulation needs to match the specific characteristics of cancer and treatment, and the development of precise methods requires researchers to gain an in-depth understanding of the mechanisms of metabolic weakness in each cancerin this review,, researchers delved into the therapeutic potential for regulating fat, carbohydrate, and protein diets, with particular emphasis on selective lysis on individual amino acid strategies, analyzed how to combine dietary strategies with other therapies to maximize their efficacy, and discussed the importance oftumorsmicroenvironments and the body-like response to the body's nutritional interventionsThe researchers discussed "diet health and cancer therapy," "hunger and calorie restriction," "precise nutrition strategies for cancer treatment," "how to balance fats and carbohydrates, and protein limits."Photo credit: Myl?ne Tajan, et alCancer Cell(2020) doi:10.1016/j.ccell.2020.04.005
Scientists have made significant progress in developing models that predict therapeutic synergies between dietary interventions and drug treatments, although there are still many questions about how best to use dietary regulation strategies to support conventional and targeted therapies; To some extent, the widespread use of cell media does not seem to reflect the environment in which cancer cells are exposed, for example, a uric acid that is richer in normal circulation than in the medium can support tolerance to 5-fluorouride, and as researchers develop more accurate physiological models to study the effects of circulating nutrients on cancer cells, researchers can now use dietary intervention strategies to identify more potential susceptibility to cancer cells, like all therapies, cancer cells are still resistant to dietary nutrition rejection strategies, but this requirestumorscell metabolic patterns (such as driving an increased synthesis pattern) or further systemic changes that can lead to targeted susceptibility (such as providing alternative resources to limit nutrition), combining dietary intervention strategies with conventional chemotherapy or having a broad effect on multiple cancer cell types, which may help reduce the risk of toleranceanother factor to consider is that dietary interventions will lead to a systemic response that is not limited to the tumor itself, but this may have an impact on other matrix "roles", such as the immune system and systemic balance, so a comprehensive analysis of the effects of dietary restrictions is aimed at maintaining a functional anti-tumor immune response and taking steps to avoid malignant lesions, but we need to take steps to avoid malignant lesionsKeep in mind that dietary interventions for cancer treatment may be short-term and should be coordinated with other treatment options, and that limiting dietary time may also reduce unnecessary side effects and improve patient compliance
;concluded that a deeper understanding of how diet affects the interactions between cancer, microenvironments, and systemic metabolism of the body may help researchers develop new strategies to treat cancer patients, while also removing recommendations for nutritional intake to help maximize the effectiveness of cancer therapy(BioValleyBioon.com)references:Myl?ne Tajan, Karen HVousden,roaches to Cancer Therapy,Cancer Cell (2020) doi: 10.1016/j.ccell.2020.04.005
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