Canadian study finds new way to fight off viruses such as influenza

McGill University in Canada has discovered a method that improves the natural resistance of biological tissue to viruses, which can effectively make biotissue cells immune to influenza and other virusesThe findings were published in the recent British journal NatureA virus is a sub-microscopic infectious intermediary that can only replicate itself through the ability of cells to replicateThis replication process usually leads to theofdiseases and even the death of the biological tissue itselfInterferons, especially type 1 interferon, have the ability to limit the reproduction of virusesThe type 1 interferon is controlled by interferon-regulating protein 7 (lrf7), which researchers believe is the main regulator of interferon production in the bodyResearchers at McGill University found that the protein synthesis of lrf7 is controlled by two inhibitory genes, 4E-BP1 and 4E-BP2In the experiment, researchers removed the two genes that prevented protein interferon production from miceBy removing both genes, mouse cells are able to produce higher levels of interferon, which can effectively prevent the virus from replicating itselfThe researchers used the method to test influenza viruses, myocarditis viruses, herpes-based styritis viruses, and so onThe researchers say this seems to be very simple in principle, but when the inhibition is removed, there will be more key proteins, lrf7, which causes an antiviral state to form inside the cellThe researchers did not find any abnormalities or side effects of increasing interferon production in laboratory mice, and they knew that it was impossible to remove both genes completely from the human body, but the researchers were optimistic that they would use their research to find new treatments for the virusIf drugs can be used to fight both genes, people can be protected from the virusAt present, although the drug does not exist, but this is the future direction of research(Du Huabin)