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Can Universal CAR-T Cross Brain Tumor "No Man's Land" DJS

 Last Update: 2022-09-06
 Source: Internet
 Author: User

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Written by Cheng Long

In the field of cell therapy, universal CAR-T (UCAR-T) has shown broader therapeutic prospects, but the allogeneic rejection limits the application of UCAR-T in the field of tumors, especially solid tumors

At present, MT-026, the fastest-growing general-purpose CAR-T cell therapy of Maoxing Bio, has shown good safety and efficacy data in an investigator-initiated clinical trial (IIT), targeting the brain glia.

"Through the CRISPR/Cas9 gene editing method, the company can make the cells remain highly viable after editing, and allow them to coexist with the patient's immune cells, achieving in vivo survival far beyond 30 days, providing a prerequisite for the treatment of solid tumors

Putting applied research experience into practice

During Shang Xiaoyun

Total issue 1696

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