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Breakthrough in development of oral insulin tablets

 Last Update: 2022-09-07
 Source: Internet
 Author: User

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change the way of administration

Injecting insulin is not a comfortable and convenient way for people with type 1 diabetes

A research team from Canada has designed an oral administration method that is absorbed through the oral mucosa with innovative ideas, and achieved good results in animal experiments

"Even two hours after dosing, we didn't find any insulin in the stomachs of the rats we tested

Briefly, the authors used an ionic crosslinking method to crosslink chitosan and sodium tripolyphosphate in a solution mixed with insulin to prepare insulin-loaded nanoparticles

Professor Anubhav Pratap-Singh said: "These exciting results show that we are on the right track in developing an insulin formulation that no longer requires injections before each meal, which will improve the The quality of life and mental health of people with diabetes

Potentially Broad Benefits

The study has not yet entered human trials, and Dr Pratap-Singh said they need more time, funding and collaborators

Yigong Guo, Alberto Baldelli, Anika Singh, Farahnaz Fathordoobady, David Kitts, Anubhav Pratap-Singh.

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