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    Home > Active Ingredient News > Antitumor Therapy > Br J Cancer: Observational cohort study reveals the effect of chemotherapy on elderly patients with early breast cancer

    Br J Cancer: Observational cohort study reveals the effect of chemotherapy on elderly patients with early breast cancer

    • Last Update: 2021-05-31
    • Source: Internet
    • Author: User
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    During 2014–2016, more than 18,500 women over the age of 70 were diagnosed with breast cancer in the UK each year , accounting for 34% of all diagnosed patients.


    During 2014–2016, more than 18,500 women over the age of 70 were diagnosed with breast cancer in the UK each year , accounting for 34% of all diagnosed patients.


    Current research shows that the benefits of chemotherapy in elderly patients are controversial.




    This multi-center, prospective, observational study aims to determine the chemotherapy (± trastuzumab) use rate, survival rate, and quality of life outcomes for EBC patients ≥ 70 years of age.




    Related research flow chart

    Related research flow chart

    Researchers performed chemotherapy on 27.




    Kaplan-Meier curve analysis of patients' survival rate and metastatic recurrence rate

    Kaplan-Meier curve analysis of patients' survival rate and metastatic recurrence rate

    All in all, the results of the study revealed that chemotherapy is associated with a reduced risk of metastasis and recurrence, but the survival benefit was only observed in ER-negative patients.


    The results of the study revealed that chemotherapy is associated with a reduction in the risk of metastasis and recurrence, but the survival benefit was only observed in ER-negative patients.



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