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BPA exposure in the placenta affects fetal brain development

 Last Update: 2022-01-22
 Source: Internet
 Author: User

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Rosenfeld suspects that microRNAs play a role in the effects of BPA exposure on later neurological disorders

"These microRNAs can be packaged in extracellular vesicles and can be transported to distant organs in the body," Rosenfeld said

BPA is used in many household items such as plastic water bottles and food containers, as well as epoxy coatings on metal food cans

Rosenfeld believes that changes in microRNAs in the placenta could also serve as early diagnostic biomarkers of BPA exposure

"By identifying the relationship between these microRNAs and BPA exposure to developing fetal brains, targeted therapy could ultimately help prevent or reverse some of the deleterious effects of BPA exposure to these microRNAs," Rosenfeld said

Future plans for this work include studying the relationship between the placenta and the brain in vitro through the use of cell culture systems

This latest finding continues Rosenfeld's decade-long interest in the effects of BPA exposure

Journal Reference :

Jiude Mao, Jessica A Kinkade, Nathan J Bivens, Cheryl S Rosenfeld.

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