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    Home > Active Ingredient News > Study of Nervous System > BMJ: Taking antidopaminergic antiemetics is associated with increased risk of ischemic stroke

    BMJ: Taking antidopaminergic antiemetics is associated with increased risk of ischemic stroke

    • Last Update: 2022-04-23
    • Source: Internet
    • Author: User
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    In large observational studies, central antidopaminergic antipsychotics were associated with an increased risk of ischemic stroke, especially in the elderly and demented populations.
    Return to normal levels after a month
    .


    Non-antipsychotic dopamine receptor antagonists, such as antidopaminergic antiemetics (ADAs), are also widely used in clinical practice, which act on peripheral blood D2 receptors


    We conducted a case-control study to identify ischemic stroke risk associated with antidopaminergic antiemetic (ADA) use


    The odds ratio for stroke was 3.
    12 in patients receiving ADA compared with controls


    Stroke risk highest on first day of ADA medication

    Stroke risk highest on first day of ADA medication Highest stroke risk on first day of ADA medication

    The study found that the use of antidopaminergic antiemetics was associated with an increased risk of ischemic stroke, with metoprazine and metoclopramide having the highest risk
    .



    Use of antidopaminergic antiemetics was associated with an increased risk of ischemic stroke, with metoprazine and metoclopramide having the highest risk
    .
    Use of antidopaminergic antiemetics was associated with an increased risk of ischemic stroke, with metoprazine and metoclopramide having the highest risk
    .

    Original source:
    Risk of first ischaemic stroke and use of antidopaminergic antiemetics: nationwide case-time-control study.
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