BMJ: Study of tumor risk in people who accidentally lost weight.

Recently, researchers quantified the predicted value of unexpected weight loss (WL) for tumor diagnosis based on the patient's age, sex, smoking status, and clinical characteristics (symptoms, signs, and abnormal blood test results).
researchers analysed the UK's National Cancer Registry for Primary Care, with a total of 63,973 adults reporting unexpected weight loss between 1 January 2000 and 31 December 2012.
of the study was tumor diagnosis within 6 months of unexpected weight loss.
of the 63,973 adults who accidentally lost weight, 37,215 (58.2%) were women, 33,167 (51.8%) were 60 years of age or older, and 16,793 (26.3%) had smoked.
908 people (1.4%) were diagnosed with tumours within six months, of whom 882 (97.1%) were over 50 years of age.
total of 10 tumor risk factors associated with accidental weight loss in men and 11 in women.
Among the tumor risk factors for accidental weight loss in men, the lowest risk factor was non-cardiac chest pain (1.86), the highest risk factor was abdominal lumps (6.10), and among the tumor risk factors for women who accidentally lost weight, the lowest risk factor was low back pain (1.62) and jaundice (20.9).
tumor-related abnormal blood test results included low albumin levels (4.67), plate plate plate abnormalities (4.57), abnormal blood calcium (4.28), abnormal white blood cell totals (3.76) and elevated C-reactive proteins (3.59).
in daily care, the risk of developing tumors in people with accidental weight loss is less than 2%, but some patients need to be alert to tumor risk if they have specific clinical characteristics.
.