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On February 28, 2022, Blueprint Medicines announced a strategic collaboration with Proteovant Therapeutics, a Roivant Sciences company, to discover and develop novel targeted protein degradation therapies aimed at addressing unmet medical needs in cancer and hematological diseases
Proteovant harnesses the protein degradation process to discover and develop transformative medicines, aided by cutting-edge computational tools such as artificial intelligence (AI) and advanced machine learning models
The collaboration will combine Proteovant's AI-based Targeted Protein Degradation (TPD) technology platform with Blueprint Medicine's expertise in precision medicine to discover novel targeted protein degradation agents
Under the terms of the agreement, Proteovant will receive an upfront payment of $20 million and will be eligible to receive up to an additional $632 million in potential research, development, regulatory and commercialization milestone payments, as well as tiered licenses for future net product sales from the first two programs royalties
References:
[1] Blueprint Medicines and Proteovant Therapeutics Announce Strategic Collaboration to Advance Novel Targeted Protein Degrader Therapies.
(Original abridged)