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Blood Cancer J: Is R-CEOP the first choice for patients with anthracycline DLBCL who are not suitable for first-line treatment?

 Last Update: 2022-09-20
 Source: Internet
 Author: User

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R-CHOP is the standard protocol for diffuse large B-cell lymphoma (DLBCL), but as with all anthracyclines, doxorubicin has dose-dependent cardiotoxicity, particularly in patients with congestive heart failure and in patients with previous exposure to

However, it is unethical to perform RCTs in patients who are not candidates for anthracycline therapy, as patients randomly assigned to the doxorubicin group experience severe cardiotoxicity due to their cardiac insufficiency and therefore tendance score matching

Research design

References

Diana Al-Sarayfi,et al.

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