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    Home > Medical News > Latest Medical News > BeiGene initiates a phase 1 clinical trial of HPK1 inhibitor

    BeiGene initiates a phase 1 clinical trial of HPK1 inhibitor

    • Last Update: 2021-03-21
    • Source: Internet
    • Author: User
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    Source: Guanlan Pharmaceutical

    Recently, BeiGene announced that a phase 1 clinical trial of its in-development hematopoietic stem cell kinase 1 (HPK1) inhibitor BGB-15025 has completed its first patient administration.


    HPK1 is a key negative feedback regulator of T cell receptor (TCR) signaling and is believed to play a key role in the anti-tumor immune response.


    The press release shows that the first phase 1 clinical trial in humans launched this time aims to evaluate the safety, tolerability, and pharmacokinetics of BGB-15025 as a single agent or in combination with Bezan in patients with advanced solid tumors.


    Note: The original text has been deleted

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