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Bayer's first-in-class therapy is approved for alleviating the progression of chronic kidney disease and reducing cardiovascular risk

 Last Update: 2021-09-06
 Source: Internet
 Author: User

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On the 10th, Bayer announced that the U.

Even if they receive the treatments recommended by the guidelines, many type 2 diabetes patients with CKD are still at risk of CKD disease progression and cardiovascular events

Kerendia is a selective mineralocorticoid receptor antagonist, which can block the excessive activation of mineralocorticoid receptor (MR)

▲Kerendia molecular structure (picture source: The Titou / Public domain)

This approval is based on the results of the pivotal Phase 3 clinical trial FIDELIO-DKD

▲The effect of Finerenone and placebo on renal function (A, B, C) and cardiovascular events (D)

"Chronic kidney disease associated with type 2 diabetes has serious disabling effects on patients' lives

Reference materials:

[1] Bayer's KERENDIA® (finerenone) Receives US FDA Approval for Treatment of Patients with Chronic Kidney Disease Associated with Type 2 Diabetes.

[2] George L.

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