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    Home > Biochemistry News > Biotechnology News > AstraZeneca's long-acting antibody cocktail therapy has positive results in the treatment of COVID-19 Phase III

    AstraZeneca's long-acting antibody cocktail therapy has positive results in the treatment of COVID-19 Phase III

    • Last Update: 2021-11-05
    • Source: Internet
    • Author: User
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    Article source: Medical Rubik's Cube Info

    Author: Shi Bei

    On October 11, AstraZeneca announced that the long-acting antibody (LAAB) cocktail therapy AZD7442 has achieved positive and high-level results in the Phase III TACKLE trial for the treatment of COVID-19


    AZD7442 is a combination of two long-acting antibodies, tixagevimab and cilgavimab


    TACKLE is a phase III randomized, double-blind, placebo-controlled, multi-center trial designed to evaluate the safety and effectiveness of a single intramuscular injection of 600 mg AZD7442 compared with placebo in the outpatient treatment of COVID-19


    The trial reached the primary endpoint.


    In a pre-specified analysis of subjects who received treatment within 5 days of the onset of symptoms, AZD7442 reduced the risk of progression to severe COVID-19 or death (for any reason) by 67% compared with placebo.


    AstraZeneca said it will discuss the data with health authorities


    Note: The original text has been deleted

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