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AstraZeneca/Mersk’s Lynparza combined with Roche Avastin is recommended in the UK for the treatment of ovarian cancer

 Last Update: 2021-04-27
 Source: Internet
 Author: User

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CompileKe Ke

Recently, foreign media reported that the National Institute of Health Care Excellence (NICE) recommended AstraZeneca/Mersk’s Lynparza (Olabarib) and Roche’s Avastin (bevacizumab) through the Cancer Drug Fund (CDF).

This recommendation is based on data from the phase 3 clinical study PAOLA-1.

In this study, about 48% of patients were newly diagnosed patients with HRD-positive advanced ovarian cancer.

The British National Health System (NHS) supports the introduction of olaparib combined with bevacizumab therapy, and the organization is providing genomic HRD testing for patients who use the therapy for the first time.

Olabarib is known as a PARP inhibitor as an inhibitor of poly ADP ribose polymerase (PARP).

In December 2014, the European Medicines Agency (EMA) and the U.

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