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Recently, the well-known journal of medicinal chemistry under the American Chemical Society, " Journal of Medicinal Chemistry " ( Journal of Medicinal Chemistry ) published an online publication of the team of Associate Professor Xiao Yuling and Professor Hong Xuechuan of our school in the near infrared second zone ( NIR-II , 1000-1700 nm ) The latest research results in the design of molecular long circulating tumor imaging fluorophores and surgical navigation resection
.
Paper entitled " self-assembling long blood circulation near infrared region of two small molecule fluorescent probes for cancer imaging and imaging-guided surgery " ( Self-Assembled with the NIR fluorophores-II.
Using conventional preoperative imaging, two-hand palpation and visual inspection, it is still a great challenge to completely remove the remaining 1%-2% of the tumor tissue without causing damage to the surrounding tissues
.
In order to overcome this limitation, some new technical methods have been introduced in the clinical treatment of cancer, such as real-time near-infrared ( NIR-I, 700-900 nm ) fluorescence image-guided surgical navigation