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Rac and Cdc42* are widely studied low molecular weight G proteins that regulate the ability of cancer cells to move, termed their motility and invasiveness
Until now, the motility and invasive ability of cancer cells have only been assessed by a biochemical method called the Rac/Cdc42 pull-down assay
Fortunately, a research team consisting of Prof.
The researchers used a recently developed non-contact stirring technique that uses an alternating electric field to "stir" droplets at extremely high speeds
Their assessment revealed many insights into cellular Rac/Cdc42 activity
According to Associate Professor Masumi Tsuda, "When developing this technique, we initially found it difficult to suppress the staining background and detect specific signals
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