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ASM Biotech declares the third domestic CD20/CD3 double antibody

 Last Update: 2021-05-08
 Source: Internet
 Author: User

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On April 27, the CDE official website showed that the clinical trial application for the EX103 injection of the CD20/CD3 bispecific antibody from Esmilion was accepted by the NMPA.

EX103 is developed using ExMab, a four-chain bispecific antibody platform from Esmin Biotech.

The EX103 of ASM Biologics is the fourth CD20/CD3 bispecific antibody to be declared clinically in China.

Roche developed a new type of "2:1" double antibody against glofitamab, which contains 2 Fabs that bind CD20 and 1 Fab that binds CD3.

mosunetuzumab is another CD3/CD20 double antibody developed by Luo.

REGN1979 was developed by Regeneron.

REGN1979

Domestic companies, Nuocheng Jianhua, Jiahe Biological, and Bojin Biological have also deployed CD20/CD3 dual antibodies, which are currently in the preclinical development stage.

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