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ASCO Amgen's innovative first-line treatment for gastric cancer reduces the risk of death by 40%

 Last Update: 2021-06-10
 Source: Internet
 Author: User

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On June 5th, Amgen announced the latest results of its investigational anti-FGFR2b monoclonal antibody therapy bemarituzumab in a phase 2 clinical trial at the ASCO annual meeting.

Gastric cancer is the fourth leading cause of cancer deaths in the world.

Bemarituzumab is a monoclonal antibody against FGFR2b.

▲The mechanism of action of bemarituzumab (picture source: Five Prime official website)

In this phase 2 clinical trial, the bemarituzumab combination therapy was more effective in a subgroup of patients with >10% of tumor cells overexpressing FGFR2b.

In terms of safety, the number of adverse events in the bemarituzumab+ chemotherapy group (100%) and the chemotherapy group (98.

Dr.

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