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    Home > Active Ingredient News > Immunology News > Arthritis Rheumatol: Efficacy and safety of anakinra in the treatment of gout attacks

    Arthritis Rheumatol: Efficacy and safety of anakinra in the treatment of gout attacks

    • Last Update: 2021-08-27
    • Source: Internet
    • Author: User
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    Anakinra is a human interleukin-1 receptor antagonist produced by genetic recombination technology


    Anakinra is a human interleukin-1 receptor antagonist produced by genetic recombination technology



    This is a multicenter, randomized, double-blind study to include not suitable for use in patients with non-steroidal anti-inflammatory drugs and colchicine treatment, follow-up of 2 years


    The results are as follows: 165 patients were enrolled , including anakinra (n = 110) or triamcinolone acetonide (n = 55)


    The results are as follows: 165 patients were enrolled , including anakinra (n = 110) or triamcinolone acetonide (n = 55)




    It can be seen that anakinra is not superior to triamcinolone acetonide in terms of the primary endpoint, but its pain reduction effect is equivalent to that of triamcinolone acetonide, and it performs better in most secondary endpoints


     

     

     

    Original source:

    Original source: Original source:

    Kenneth G.


    Kenneth G.
    Saag.
    A Randomized, Phase II Study Evaluating the Efficacy and Safety of Anakinra in the Treatment of Gout Flares.
    Arthritis Rheumatol.
    August 2021.
    A Randomized, Phase II Study Evaluating the Efficacy and Safety of Anakinra in the Treatment of Gout Flares .


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