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Arthritis Rheumatol: Analysis of the incidence of psoriatic arthritis in patients receiving biotherapy for psoriasis

 Last Update: 2021-09-03
 Source: Internet
 Author: User

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Recently, rheumatism immunity journal Arthritis field of authority published a research article on & Rheumatology, the study was designed to investigate the treatment of psoriasis biological effect on the incidence of psoriatic arthritis
.

immunity

The researchers used the electronic medical records of large health maintenance organizations to conduct a retrospective cohort study
.

Patients who have received biotherapy for psoriasis and have not been diagnosed with psoriatic arthritis before or at the start of biotherapy are included

diagnosis

The study included a total of 1326 patients; 663 patients who had received biologic therapy and 663 patients who had not received biologic therapy
.

The Kaplan-Meier curve of the propensity score matching group reflects a statistically significant increase in the risk of psoriatic arthritis in the control group compared with the biological treatment group

Multivariate Cox regression results showed that compared with the biological treatment group, the control group had a significantly higher risk of developing psoriatic arthritis (adjusted HR=1.
39; 95%CI: 1.
03-1.
87)
.

The risk of psoriatic arthritis in patients with psoriasis receiving biologic drug treatment is statistically and clinically significantly reduced

Original source:

Yael Shalev Rosenthal,et al.

Psoriatic arthritis incidence among patients receiving biologic medications for psoriasis: A nested case control study .
Arthritis Rheumatol.
2021.
https://onlinelibrary.

Psoriatic arthritis incidence among patients receiving biologic medications for psoriasis: A nested case control study

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