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OBJECTIVE : Previous studies have demonstrated that lower levels of baseline disease activity predict favorable disease activity status
.
Furthermore, higher levels of baseline disease activity proved to be associated with greater absolute change
.
ObjectivesObjective : Previous studies have demonstrated that lower levels of baseline disease activity predict favorable disease activity status
Methods : Investigators used data from three rheumatoid arthritis (RA) trials (one for the primary analysis and two for the validation) to analyze patient and disease characteristics, core set measures, and composite index pairs to achieve different outcomes Effects of: response outcome (percentage of patients achieving relative response range); status outcome (remission or low disease activity, LDA ) and change outcome (numerical change on a metric scale)
.
Methods: Investigators used data from three rheumatoid arthritis (RA) trials (one for primary analysis and two for validation) to analyze differences in patient and disease characteristics, core set measures, and composite indices.
RESULTS: Investigators included patients from the ASPIRE trial (for analysis) and from the ATTRACT and GO-BEFORE trials (for validation)
ConclusionsConclusions : Prediction of success in RA treatment is limited
.
Source:
Capelusnik D, Aletaha D.
Baseline predictors of different types of treatment success in rheumatoid arthritis.
Annals of the Rheumatic Diseases2022; 81: 153-158.
Baseline predictors of different types of treatment success in rheumatoid arthritis.
Annals of the Rheumatic Diseases2022; 81: 153-158.
Annals of the Rheumatic Diseases81: Leave a comment here