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Application of ibidi fluid shear force system in the study of oscillating flow on the formation of lymphatic valves

 Last Update: 2022-08-30
 Source: Internet
 Author: User

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In a 2015 paper, a research group in Switzerland used the ibidi fluid shear force system and single-channel Luer slides to study the role of irregular shear forces in the lymphatic valve area and found that irregular shear forces It plays a key role in the formation of lymphatic valves

Simulate flow in lymphatic vessels

System settings:

• ibidi pump system

•μ-Slide I0.

• Oscillating flow

(4 dyn/cm2; 0.

Part of the lymphatic system consists of valved vessels that prevent lymphatic backflow.

Results: SiFOXC2 cells did not form proper adherent junctions under OSS (see VE-Cadherin immuno stain)

Amélie Sabine, the first author of the paper, states: "We need to understand the mechanisms that influence lymphatic valve development

The ibidi fluid shear force system can bring new research ideas and methods to your experiments, providing you with cell culture conditions stimulated by fluid shear force:

The ibidi fluid shear force system can simulate flow patterns in a variety of physiological states - unidirectional laminar flow, oscillating flow, pulsating flow
Compatible with incubators, suitable for long-term cultivation
Compatible with microscopes, easy to observe cells in real time
Computer software precisely controls flow rate and shear force
A variety of consumables are available, completely sterile closed design, saving the amount of medium and reagents

ibidi Fluid Shear System

Guangzhou Keshite Scientific Instrument Co.

If you are interested please contact us

Tel: 020-38102730

Service QQ: 501747125

Email: info@kosterscience.

Address: Room D, Room 140, North Tower, Junhui Building, Tiyu West Road, Tianhe District, Guangzhou

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