Apple peel extract can delay the aging process

"An apple a day keeps the doctor away from you" is a well-known health proverb However, the best way to eat apples is to take the skin with you According to the latest issue of Nature Medicine, US researchers found that the combination of dasatinib (a leukemic drug) and quercetin (an extract from apple peel) can prolong the life span of old mice by 36% Senescent cells usually appear in the human body in their 60s, but earlier in obese or chronic patients These abnormal cells are in a state of decline, but they are not willing to die It is believed that aging cells themselves can catalyze the process of aging A team led by James Cochran of the Mayo Clinic in the United States has shown that this is indeed the case When the researchers injected a small amount of senescent cells into six-month-old mice, their speed, endurance and strength decreased by 20% to 50% in a few weeks, almost the level of a typical two-year-old mouse To block the effects of aging cells, the team chose a combination of dasatinib and quercetin, both of which interfere with the way aging cells avoid death When the team gave the combination to mice that had aged from the injection of senescent cells, the mice recovered 50% to 100% of their lost physical ability within two weeks When the team gave the drug to older mice aged 24 to 27 months, the speed, endurance and strength of these mice increased by 30 to 100%, and their remaining life span was 36% longer than that of those without the drug.