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Parkinson's disease (PD) is the second progressive neurodegenerative disease and the most common chronic disease in the world after Alzheimer's disease (AD)
.
Neuroprotection in Traditional Chinese Medicine (TCM) has been used in alternative medicine since its early days
Traditional Chinese medicine-derived neuroprotective compounds, such as chrysin, cannabidiol, Toonasinoids, and beta-asarone, have shown significant efficacy in Parkinson's disease (PD)
Summary of PD prevalence in the Chinese population compared to Europe, and a meta-analysis of global PD prevalence, including cost per PD patient:
Summary of PD prevalence in the Chinese population compared to Europe, and a meta-analysis of global PD prevalence, including cost per PD patient:Methods: Relevant information on neuroprotective TCMs was collected from scientific databases (PubMed, Web of Science, Google Scholar, ScienceDirect, SciFinder, Wiley Online Library, ACS Publications, and CNKI)
.
Information is also obtained from MS and Ph.
method:
Possible mechanisms of mitochondrial dysfunction leading to PD through ROS :
Possible mechanism of mitochondrial dysfunction leading to PD through ROSPossible mechanisms of oxidative stress in PD via ROS:
Possible mechanisms of oxidative stress in PD via ROS:RESULTS: Novel therapies for PD are available, mainly relying on rivastigmine and donepezil, which can slow disease progression in the early stages, but suffer from a number of drawbacks
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Researchers are trying to find a potential anti-PD drug that could effectively prevent or cure disease progression, but further identification is needed
result:
To sum up, TCM components play an active role in enhancing immunity, promoting neurogenesis, eliminating neurotoxic proteins and repairing nerve damage in the SNPc region of the brain through anti-apoptotic, anti-inflammatory and antioxidant pathways
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It should be emphasized here that TCM belongs to the logical discussion in the scientific medicine system, which is considered to be a common concept and syndrome difference
TCM components play an active role in enhancing immunity, promoting neurogenesis, eliminating neurotoxic proteins, and repairing nerve damage in the SNPc region of the brain through anti-apoptotic, anti-inflammatory and antioxidant pathways
Original: Muhammad F, Liu Y, Zhou Y, Yang H, Li H.
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