Antibiotics prevent children from dying of bis;

two researchers at the National Brain Research Center found that a broad-spectrum antibiotic called metamine tetracycline is effective in preventingchildren fromdying of epidemic encephalitisExperts say the findings may change the medical community's treatment of the brain b has been mainly prevention, but no good treatmentThe findings are published in the forthcoming issue of the journal NeurochemistryEpidemic encephalitis B (b brain) is an acute infectious disease of the central nervous system, with a fatality rate of 3% to 10%Its pathogen was discovered in Japan in 1934, so it is internationally known as Japanese encephalitis BIn 1938 scientists determined that it was transmitted by mosquitoes as a vector and was a natural source of zoonotic diseasesdiseasesThe disease is more common in children under 10 years of age, because of poor prevention, 30%-70% of patients who are not immune from death have serious sequelae, life-long disabilityPrevious studies have shown that the cause of the disease involves deep neuronal deletion and secondary inflammation caused by apoptosis, which has long been the only way to take support therapy and no special drug treatmentBut the medical community did not abandon the study until the effects of metformin tetracycline were discoveredHumans mainly use the hydrochloride form of metformin tetracycline, which is known for its high efficiency and long-term effectiveness, its antibacterial spectrum is similar to polycycyclin, but its antibacterial ability is superior to polycycyclin; The most powerful trait in the same class, metformin, ensures that its penetration of the blood-brain barrier is good, and the concentration is relatively high after the brain and cerebrospinal fluidTetracycline drugs tend to produce tolerance, and experts decided to test the effects of metformin in an experimental testThe 78 strains of B-brain virus were inoculated into the adult mice, and then treated with metformin tetracycline, and it was finally found that metformin could directly act on the brain cells of the mouse, and several indicators in the mouse ——— the rate of apoptosis of nerve cells, the activation rate of small glial cells, the activation activity of cysteine protease, the inflammatory media and the virus titerThe drug is so effective that researchers are satisfied that authorities are actively planning clinical trials in patients with B to further test their response sourcing in humans (Zhang Mengran)