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Anti-artemisinin malaria in Africa: gain a foothold

 Last Update: 2021-09-29
 Source: Internet
 Author: User

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In the early 2000s, the malaria parasite appeared in Southeast Asia, which could hinder artemisinin, a key component of first-line treatment

Africa is at greater risk, and it is only a matter of time before the emergence of artemisinin-resistant malaria in Africa

Patients with drug-resistant parasites only need longer time to get rid of them

Mosquito-borne parasites——Plasmodium falciparumalways thereRapid mutation

Research tracking found that drug resistance comes from a mutation in the kelch13 gene

Lancet infectious disease, Focusing on children who were taken to three medical centers in Rwanda in 2018 with fever

From 2017 to 2019, the research team studied the response of malaria patients treated with intravenous artesunate (a water-soluble artemisinin derivative) at St.

The genetic details of the two new studies indicate that this evasion drug mutation occurred locally, not imported from Southeast Asia

It was pointed out that when this kind of resistance appeared, it led to the beginning of clinical failure in Southeast Asia

Doctors in Southeast Asia use different drugs in cycles to maintain the effectiveness of combination therapy

"We shouldn't wait until the children start dying of drug-resistant parasites to solve this problem

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