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The polygenic risk score (PRS) can be used to assess the risk of an individual for a certain disease, such as coronary artery disease, breast cancer or diabetes
The polygenic risk score (PRS) can be used to assess the risk of an individual for a certain disease, such as coronary artery disease, breast cancer or diabetes
The study used genome-wide association study data from 15 585 AS patients and 20 452 controls (European and East Asian races) to develop and validate PRS
In the European population, PRS has a high distinguishing ability, and the area under the receiver operating characteristic curve (AUC) is 0.
In the European population, PRS has a high distinguishing ability, and the area under the receiver operating characteristic curve (AUC) is 0.
In short, compared to only examining CRP, sacroiliac MRI or HLA-B27, PRS is more capable of distinguishing AS
Original source:
Original source: Original source:Zhixiu Li.
Zhixiu Li.
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