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Many patients with rheumatoid arthritis (RA) use glucocorticoid (GC) alone to treat poorly and need to be combined with other anti-rheumatic drugs
.
An article recently published in Ann Rheum Dis, a leading journal of rheumatology, described the dynamic trajectory and characteristics of GC reduction and drug withdrawal in RA patients after starting GC combined with conventional synthetic disease improving antirheumatic drugs (csDMARDs)
Many patients with rheumatoid arthritis (RA) use glucocorticoid (GC) alone to treat poorly, and need to be combined with other anti-rheumatic drugs
The study used real targeted therapy data from the RA cohort
.
The RA patients who started the combination therapy of GC and csDMARDs were included
The study used real targeted therapy data from the RA cohort
The results are as follows: A total of 207 RA patients were included
.
During a median follow-up of 38.
The results are as follows: A total of 207 RA patients were included
Figure: Kaplan-Meier analysis curve of the cumulative probability of hormone withdrawal
Figure: Kaplan-Meier analysis curve of thecumulative probability of hormone withdrawal.Figure: Kaplan-Meier analysis curve of the cumulative probability of hormone withdrawal
It can be seen that for RA patients who started GC combined with csDMARDs treatment, GC can be stopped, and disease activity is well controlled, and most patients have no seizures in a short period of time
.
However, the drug withdrawal time is far from the recommended time range, which indicates that there is a gap between the actual clinical practice and the current guidelines
It can be seen that for RA patients who started GC combined with csDMARDs treatment, GC can be stopped, and disease activity is well controlled, and most patients have no seizures in a short period of time
Original source:
Original source: Original source:Wenhui Xie.
Wenhui Xie.
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