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At present, for patients with acute ischemic stroke (AIS) with large vessel occlusion (LVO), moderate to severe clinical dysfunction but no large area of irreversible damage to the tissue ("core") , if treatment can be carried out in the early time window, it is recommended to use Mechanical thrombectomy (MT), not just the best medical management .
Thrombosis Management in Vascular Stroke
The team hypothesized that patients with large cores who have a large number of persistent penumbras would benefit from MT, but those patients whose imaging revealed completed infarction would not
They compared LVO-related patients in the two cohorts with larger cores (diffusion-weighted imaging or CT perfusion using RAPID> 50 ml), perfusion imaging, and a prospective study within 6 hours after the onset MT+Best Medical Management (BMM) treatment, or only BMM treatment in the pre-MT era in a prospective registry
They included 107 patients (56 MT+BMM+51 BMM)
MMRatio strongly changed the clinical outcome after MT (continuous MMRatio, p-interaction<0.
MMRatio strongly changed the clinical outcome after MT MMRatio strongly changed the clinical outcome after MT
In patients with MMRatio>1.
Similar findings were found in the subgroup with core part ≥ 70 ml, MMRatio ≥ 1.
Similar findings were found in the subgroup with core part ≥ 70 ml, MMRatio ≥ 1.
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