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Today, ASBMB Today published an article introducing the so-called Targeting 20,000 proteins by 2035 (asbmb.
Drug source analysis
Drug source analysisThe human genome has about 20,000 genes.
In addition to active and selective probes, other properties also need to meet certain standards, such as water solubility at least to ensure sufficient drug dissolution in cell experiments, and chemical stability at least to a certain degree within the experimental time scale.
Of course, there are also some small molecule technological advances that make this goal easier to achieve.
Although this goal is very ambitious and faces various problems, it is better than nothing.