An antifungal drug that could help destroy dormant cancer cells in intestinal tumors, study finds

scientists at the University of Cambridge's Cancer Research Centre have found that an antifungaldrug used to treat nail infections(or help eliminate dormant cancer cells in intestinal tumours)study published in the international journal Of The International Medicineresearchers in mice found that the drug, called isoconazole, can be effective in slowing the growth and progression of certain types of bowel cancer, and the next step is to look at whether the drug is also effective in the body of bowel cancer patientsresearchers identified two key pathways involved in cell sleep and used microintestinal tumors derived from cells from cancer mice todetect the effects of(targeting these pathways)researchers have found for the first time that the antifungal drug Isoconazole blocks the Wnt signaling pathway and blocks the growth of tumors in mice, while also eliminating dormant cancer cells, which can be involved in the growth and spread of multiple cancersthe next step in the researchers will be to test the effects of isoconazole in the human body, the researchers hope to be able to conduct clinicaltrials as soon as possible
(to test the effects of isoconazole in the treatment of malignant bowel cancer patients, and they also want to study whether the drug can be combined with treatments such as chemotherapy.)the findings are expected to help researchers address a huge challenge in cancer research, which is made up of many types of cancer cells that can evolve separately and respond differently to therapy