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A recently proposed mechanism is insufficient arousal due to loss of wake-promoting neurons and neurotransmitters associated with tau tangles, one of the pathological hallmarks of AD, resulting in sleep-wake disturbances and a higher propensity for daytime naps
However, in previous studies, there are still conflicting results regarding the impact of daytime naps on cognition
However, all previous studies assessed each participant with only one nap
From this, Peng Li et al.
They found that older adults tended to take longer and more frequent naps as they aged, and Alzheimer's progression accelerated this change, more than doubling the number/frequency of naps per year
Longer and more frequent daytime naps are associated with a higher risk of Alzheimer's dementia
Longer and more frequent daytime naps are associated with a higher risk of Alzheimer's dementia
aytime napping and Alzheimer's dementia: A potential bidirectional relationship.
Alzheimer's & Dementia.
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