Alzheimer's Dementia: Data on 60 million people in the United States has found that the risk of new crowns for people with dementia has increased dramatically

The new crown was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) and quickly escalated into a global pandemic.
severe symptoms caused by COVID-19 occur mainly in the elderly and individuals with underlying clinical conditions, such as Alzheimer's disease (AD), which is a common cause of morbidity and death in older populations.
addition, most people with dementia are accompanied by one or two additional chronic diseases.
, there is little quantitative analysis of the risks and outcomes of COVID-19 in people with AD or dementia in the United States.
estimates that millions of people 65 and older in the United States live with AD and other dementias.
cognitive decline and strong risk factors for dementia include cardiovascular disease, diabetes, obesity and high blood pressure.
common co-mergers in people with dementia are also risk factors for COVID-19 and are associated with worse clinical outcomes.
in people with dementia, including vascular dementia and AD, the blood-brain barrier (BBB) is damaged, making it easier for certain bacteria and viruses to enter the brain and making patients more susceptible to bacterial, viral and fungal infections.
addition, dementia-related memory disorders may interfere with patients' adherence to COVID-19 precautions such as social alienation, wearing masks, and frequent hand washing and disinfection.
, it is reasonable to assume that people with dementia have an increased risk of contracting COVID-19, which exceeds the predicted risk of their combined disease.
SARS-CoV2 has also been shown to directly affect the brain, with reports of encephalitis, thrombosis and brain invasion.
fact, the early signs of the disease are loss of taste and smell.
addition, the brain is affected by organ failure in other areas, such as the heart or lungs, and hypoxemia is a sign of a serious infection that can itself lead to cerebral edema and brain disorders.
As a result of these frequent brain complications and autopsy results, it can be speculated that pre-existing dementia, especially vascular damage (vascular dementia) in the brain, can put patients at greater risk of COVID-19 morbidity and death.
, another important hypothesis is that people with dementia are at greater risk of adverse outcomes if they become infected.
, the likes of Quan Wang of Case Western Reserve University explore the direct relationship between the new crown and dementia.
used electronic health records (EHRs) to conduct retrospective case-control analyses of 61.9 million adult and elderly patients in the United States (aged ≥18).
found that people with dementia had an increased risk of COVID-19 (OR 2.00) compared to those without dementia, with the greatest impact on vascular dementia (OR: 3.17), followed by Alzheimer's disease Dementia (OR 2.62), Alzheimer's disease (OR:1.86), Alzheimer's disease (OR:1.99), and post-traumatic dementia (OR:1.67).
blacks with dementia had a higher risk of COVID-19 than whites (OR:2.86, P.lt; .001).
patients with dementia with COVID-19, the six-month mortality rate and hospitalization risk were 20.99 percent and 59.26 percent, respectively.
the practical significance of this study is that it highlights the need to provide the necessary protection for people with dementia during the new crown pandemic as part of a strategy to control the COVID-19 pandemic.
original origins Of Wang, Q., Davis, P.B., Gurney, M. E., samp; Xu, R. (2021). COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US. _Alzheimer's and Dementia Freeman Source: MedSci Original Copyright Notice: All text, images and audio and video materials on this website that indicate "Source: Mets Medicine" or "Source: MedSci Originals" are owned by Mets Medical and are not reproduced by any media, website or individual without authorization, and are authorized to be reproduced with the words "Source: Met Medical".
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