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| All natural acellular matrix scaffold can repair damaged muscles |
Bioengineers from Rice University in the United States introduced a bioactive scaffold in a new study published in the journal "Science Advances" on the 14th.
The bioactive scaffold is manufactured by electrospinning in the laboratory.
This research is expected to reduce the burden of approximately 4.
"The main innovation of the research is to be able to prepare scaffolds entirely derived from extracellular matrix.
This kind of scaffold uses the biological activity cues of decellularized muscle to provide adjustable cross-linking density of the scaffold through electrospinning, thereby creating a scaffold rich in biochemical cues and highly specific morphology.
Experiments have shown that when the scaffold is not saturated with the cross-linking agent, the cell proliferation is optimal, which allows them to access the biochemical cues in the scaffold matrix.
Most of the acellular matrix used for muscle regeneration comes from thin films such as skin or small intestine tissue.
Smok said: "This bioactive scaffold can produce highly aligned fibers, very similar to the structure people find in skeletal muscle, and has all the biochemical cues needed to promote the creation of new muscle tissue.
Currently, researchers say that in addition to the use of this stent in large muscle injuries caused by sports or trauma, it is also expected to be used in craniofacial muscles.
Stent materials are very common in surgery, and it is undergoing a series of iterations.
