 Home > Active Ingredient News > Blood System > AJCP: Direct thrombin inhibitor versus activated partial thromboplastin time in pediatric patients is monitored using calibrated diluted thrombin time

AJCP: Direct thrombin inhibitor versus activated partial thromboplastin time in pediatric patients is monitored using calibrated diluted thrombin time

 Last Update: 2022-11-25
 Source: Internet
 Author: User

Tags

what 2 4

oats germination time

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Figure 3: Example of direct thrombin inhibitor monitoring test values over time in patients taking a constant dose of
argatroban.
A, diluted thrombin time (dTT).

B, activated partial thromboplastin time (aPTT).

The patient is a 7-month-old man taking argatroban for venous thrombosis in the setting of heparin-induced thrombocytopenia
.
As shown, the dose of argatroban was constant at 2.
25 μ g/kg/min
during monitoring.

Figure 4: Determination of mean Pearson coefficient for diluted thrombin time (dTT) or activated partial thromboplastin time (aPTT) compared to bivaludin or argatroban
.
A, for argatroban, dTT had a significantly higher mean correlation (r2) dose greater than aPTT (n = 10, P = .
028, one-tailed paired t-test).

B.
When agatroban and bivalutin were combined, the mean correlation of dTT was significantly higher than that of the control group (r2) at doses greater than aPTT (n = 14, P = .
007, single-tailed paired t-test).

Original source:

Hasan RA, Pak J, Kirk CJ, Friedland-Little JM, Chandler WL.
Monitoring Direct Thrombin Inhibitors With Calibrated Diluted Thrombin Time vs Activated Partial Thromboplastin Time in Pediatric Patients [published online ahead of print, 2022 Nov 9].
Am J Clin Pathol.
2022; aqac131.
doi:10.
1093/ajcp/aqac131

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Gadusol Powder Gadusol76663-30-4

CAS No.: 76663-30-4

Industrial Grade

$1-1.01/G FOB

Food Additive Iron fumarate for Nutritional Iron Supplements

CAS No.: 141-01-5

Pharmacy Grade

$24-26/G FOB

Aminobenzoic Acid CAS 56-91-7

CAS No.: 56-91-7

Pharmaceutical Grade

$100/KG EXW

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.