Advances in the study of atrophy-based lateral sclerosis vaccine

Japanese and Canadian researchers have developed a vaccine against inherited amyotrophic lateral sclerosis and successfully extended the lifespan of mice in animal experimentsResearchers at Shiga Medical University in Japan and others report in the online edition of the Proceedings of the National Academy of Sciences that they injected the vaccine,with an average life span of about 13 months, for the 11th month of lifeIt was found that,themice had aof about2
0 days later than the unvaccinated control group, and thelife span was about 30 days longer,after receiving the vaccineThe researchersthe gene thatsynthesizing the "SOD1" enzyme is thought to be linked to the onset of amyotrophic lateral sclerosisTheir studythat the "SOD1" enzyme, whichshould have existed in the cytoplasm, "transfers" out of the cell because of genetic mutations, damagingmovementnerves, gradually triggering amyotrophic lateral sclerosisUsing Ecoli for genetically modified operations, the researchers synthesized an inactive "SOD1" enzyme, which was used as a major ingredient to make a vaccine and inject it into laboratory miceThe vaccine mainly reacts with the mutated "SOD1" that prevents the latter from functioningAmyotrophic lateral sclerosis is aofdiseases that cause the progressive degeneration of neuronal cells in themotor, of which about 10% are hereditary casesEarly symptoms of the patient mainly manifest themselves as weakness in the hands and feet or lower limb spasms, and thendiseasegradually spread to the main muscles of the body, and the patient may eventually die of breathing difficultiesHawking, a famous British scientist, is a patient with amyotrophic lateral sclerosis (
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